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10 known side effects of HRT: 1. Breast tenderness or swelling in the first few weeks to 3 months. 2. Increased breast density in the first 1–2 years, which can make mammograms harder to interpret. 3. Combined HRT slightly increases breast cancer risk after 5 years (4–8 extra cases per 1,000 women). 4. Irregular bleeding or spotting in the first 3–6 months. 5. Nausea or bloating, especially with oral forms. 6. Headaches or migraines in some women. 7. Mood changes—some feel calmer, others more ir
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