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Karen and CJ ● Certified Dog Behavior Consultant on Instagram: "Knuckling in the rear paws is often one of the earliest observable signs of Degenerative Myelopathy (DM). This happens because DM primarily affects the white matter of the spinal cord, the area responsible for transmitting signals between the brain and the limbs. As the disease begins, the nerve fibers in the white matter start to deteriorate. When those communication pathways weaken, the rear paws may not receive accurate informati
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