Genetic Conditions and Testing — Irongate Equine Clinic
Genetic Conditions and Testing — Irongate Equine Clinic
May 16, 2019
irongateequine.com
Diagnosis: Rhabdomyolysis Rhabdomyolysis (commonly called “tying-up”) can occur for a number of reasons in horses including over-exertion, muscle trauma, nutritional or electrolyte imbalance, or extreme fatigue. Quarter horses and related breeds have been genetically linked to a number of conditions that can result in rhabdomyolysis including HYPP and PSSM1. Rhabdomyolysis is initially treated with sedation to allow the horse to relax and NSAIDs to relieve muscle pain. Horses should have blood w
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Diagnosis: Rhabdomyolysis Rhabdomyolysis (commonly called “tying-up”) can occur for a number of reasons in horses including over-exertion, muscle trauma, nutritional or electrolyte imbalance, or extreme fatigue. Quarter horses and related breeds have been genetically linked to a number of conditions that can result in rhabdomyolysis including HYPP and PSSM1. Rhabdomyolysis is initially treated with sedation to allow the horse to relax and NSAIDs to relieve muscle pain. Horses should have blood w
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#3) Hyperkalemic periodic paralysis (HYPP) What is it? HYPP is a muscular disease caused by a genetic mutation that disrupts the sodium ion channel and results in an excessive amount of potassium in the blood (hyperkalemia). This causes the muscles to contract more readily than normal. Horses with HYPP can experience unpredictable attacks of muscle tremors or paralysis, which in severe cases can lead to collapse and sudden death due to cardiac arrest or respiratory failure What are the signs/sym
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#3) Hyperkalemic periodic paralysis (HYPP) What is it? HYPP is a muscular disease caused by a genetic mutation that disrupts the sodium ion channel and results in an excessive amount of potassium in the blood (hyperkalemia). This causes the muscles to contract more readily than normal. Horses with HYPP can experience unpredictable attacks of muscle tremors or paralysis, which in severe cases can lead to collapse and sudden death due to cardiac arrest or respiratory failure What are the signs/sym
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