GitHub - scRNA-Compt/EasyDesign: A CNN based model to …
Enhanced crRNA design system with Deep learning for Cas12a-mediated Diagnostics, termed EasyDesign. EasyDesign predicts sgRNAs based on deep learning techniques and its design …
In this study, we propose ‐ an enhanced crRNA design system with deep learning for Cas12amediated ‐ diagnostics, referred to as EasyDesign. This system employs an optimized …
Deep learning enhancing guide RNA design for CRISPR/Cas12a …
Nonetheless, the effective design of CRISPR RNA (crRNA) for Cas12a-based detection remains challenging and time-consuming. In this study, we propose an enhanced crRNA design …
A small library crRNA-enhanced CRISPR-Cas12a system for …
Jun 1, 2025 · We using the machine learning-guided crRNA design to target highly conserved viral regions, obtain the optimized crRNA sequence, and multi-crRNA collaborative signal …
EasyDesign
E nhanced crRN A design sy stem with D eep l e arning for Ca s 12a-med i ated Dia gn ostics, termed EasyDesign. EasyDesign predicts sgRNAs based on deep learning techniques and its …
This study offers new insights into the molecular interactions of Cas12a/crRNA-DNA and provides a reliable framework for optimizing crRNA design, facilitating the application of the CRISPR …
Deep learning enhancing guide RNA design for CR... - Scoop.it
Nonetheless, the effective design of CRISPR RNA (crRNA) for Cas12a-based detection remains challenging and time-consuming. In this study, we propose an enhanced crRNA design …
<br>深度学习增强基于 CRISPR/Cas12a 诊断的指导 RNA 设计 …
Jun 15, 2024 · Nonetheless, the effective design of CRISPR RNA (crRNA) for Cas12a-based detection remains challenging and time-consuming. In this study, we propose an enhanced …
EasyDesign/README.md at main · scRNA-Compt/EasyDesign
Enhanced crRNA design system with Deep learning for Cas12a-mediated Diagnostics, termed EasyDesign. EasyDesign predicts sgRNAs based on deep learning techniques and its design …
iMeta | 之江实验室/农科院基因组所联合开发CRISPR/Cas12a检测体系crRNA …
Jun 29, 2024 · 本研究开发的EasyDesign是基于CNN的Cas12a crRNA特异性设计系统，该模型在源自涵盖常见细菌和病毒病原体的高质量Cas12a检测序列的数据集上进行训练。
Enhancement of CRISPR-Cas12a system through universal circular RNA design
Jun 16, 2025 · Wang et al. present a universal circular RNA design enabling precise control of Cas12a activity via UV light or base excision repair enzymes. This system achieves high …
Deep learning enhancing guide RNA design for CRISPR/Cas12a …
Nonetheless, the effective design of CRISPR RNA (crRNA) for Cas12a‐based detection remains challenging and time‐consuming. In this study, we propose an enhanced crRNA design …
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