Monoclonal antibody - Wikipedia
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way …
Monoclonal Antibodies: Purpose, Risks & Results
Dec 10, 2025 · Monoclonal antibodies can treat autoimmune conditions, cancers and other diseases by working with your immune system.
What are Monoclonal Antibodies and how do they work? - Drugs.com
Jun 3, 2025 · The mAb (ibritumomab) delivers a radioactive substance (Yttrium-90) directly to cancer cells. Another example is Kadcyla, an mAb that is attached to a chemotherapy drug.
Monoclonal Antibodies and Their Side Effects | American ...
Bevacizumab (Avastin) is an mAb that targets a protein called VEGF that affects tumor blood vessel growth. It can cause side effects such as high blood pressure, bleeding, poor wound …
The pharmacology and therapeutic applications of monoclonal ...
The majority of mAb therapeutics are for oncological and immunological/infectious diseases, but these are expanding into other disease areas. Over 100 monoclonal antibodies are in …
Why mAbs Matter | Quality Matters | U.S. Pharmacopeia Blog
FDA-approved mAb treatments have been available since the late 1980s. Monoclonal antibody drugs have proven to be more successful at treating certain diseases, such as some cancers, …
Overview of therapeutic monoclonal antibodies - UpToDate
Aug 18, 2025 · According to the World Health Organization (WHO), which is responsible for therapeutic mAb nomenclature, over 800 mAb names have been provided [1]. (See 'Naming …