The growth rate of the atmospheric abundance of methane (CH4) reached a record high of 15.4 ppb yr−1 between 2020 and 2022, but the mechanisms driv ...

Cell-based therapy using satellite stem cells (SSCs) holds tremendous potential for enhancing muscle regeneration. However, conventional isolation methods often yield heterogeneous cell populations ...

Many cities seek to alleviate extreme heat via planting trees. However, the cooling achieved by such programs is debated because previous analyses address scales much smaller than the whole-city scale ...

Moiré excitons in van der Waals (vdW) structures are of particular interest for both fundamental science and cutting-edge applications. The recent discovery of two-dimensional (2D) magnetic ...

Voltage-gated Nav1.5 channels are central to the generation and propagation of cardiac action potentials. Aberrations in their function are associa ...

F-type ATP synthase (F 1 F O) catalyzes proton motive force-driven ATP synthesis in mitochondria, chloroplasts, and bacteria. We have identified an architecture of F 1 F O from Chloroflexus ...

Wing dimorphism of insect vectors is a determining factor for viral long-distance dispersal and large-area epidemics. Although plant viruses affect the wing plasticity of insect vectors, the potential ...

Earth’s solid inner core exhibits intriguing characteristics such as an exceptionally low shear-wave velocity and an ultrahigh Poisson's ratio. In this study, we have used high pressure–temperature ...

We previously reported two classes of reproductive phasiRNAs (phased, small interfering RNAs) in maize, the premeiotic 21-nt (nucleotides) phasiRNAs and the meiotic 24-nt phasiRNAs. Here, we report a ...

Geological observations informed by climate dynamics imply that the oceans were 99.9% covered by light-blocking ice shelves during two discrete, self-reversing Snowball Earth epochs spanning a ...

Protein therapeutics hold immense promise for treating infectious diseases and genetic disorders. However, their efficacy is substantially limited by the challenge of delivering proteins to specific ...

KRAS G12C inhibitors have shown clinical responses in KRASG12C -mutant lung cancer, but much less so in colon cancers having the same mutation. In lung cancer, acquired resistance limits the clinical ...