Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses. A new study of 500,000 individuals indicates that people who have more copies ...

Computational and genomic tools have enabled researchers to explore the human genome and make many associations between various characteristics and genes or gene variants. But many parts of the human ...

ATRX (alpha thalassemia/mental retardation X-linked) complexes with DAXX to deposit histone variant H3.3 into repetitive heterochromatin. Recent genome sequencing studies in cancers have revealed ...

In the absence of SIRT7, a human primary cell displays multiple nucleoli. DNA was stained with DAPI (turquoise) and nucleolus was stained with anti-fibrillarin (red). Disclaimer: AAAS and EurekAlert!

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...