Syria's Islamist-led government said its security forces were deploying in the predominantly Druze southern city of Sweida on Saturday and urged all parties to respect a ceasefire after days of factional bloodshed that has left hundreds dead.

U.S. Secretary of State Marco Rubio described the situation as "complicated" but said it looked like a "misunderstanding".

Israel said it "struck the entrance of the Syrian regime's military headquarters" and warns of more "painful blows".

Israel launched massive airstrikes in Damascus, Syria, as a response to apparent attacks against the Druze minorities in Sweida. Lina Sinjab with BBC News, a CBS News partner, has more.

Israel has been carrying out strikes on Syria since the fall of the Assad regime last December. This week saw a major escalation, when Israel said it attacked Syria to protect the Druze, an Arab minority at the center of clashes with government loyalists.

As alarming sectarian violence swept through Syria in the third week of July, Christian communities in the region experienced a new wave of persecution. Attacks on the country's Christian, Druze and Alawite communities were perpetrated mainly by Islamist jihadists.

That afternoon, Netanyahu and Katz ordered the Israeli military to once again attack government forces and weaponry in Suweida. They said they were working to prevent them from harming the Druze and to "ensure the demilitarisation" of areas near Israel's border.

Violence in Syria's Druze province has triggered Israeli military action, complicating relations with Turkey and creating a power vacuum that Iran could exploit.