Interim biomarker data accepted for presentation at the 19th Clinical Trials on Alzheimer's Disease (CTAD) conferenceRecent peer-reviewed data ...

Axonal transport — the process through which neurons shuttle diverse cargoes — is fundamental for neuronal differentiation, function and survival. Disrupted axonal transport has been implicated in ...

AL-S Pharma AG, a clinical-stage biotechnology company discovering and developing human antibodies that target misfolded proteins implicated in amyotrophic lateral sclerosis (ALS), today announced the ...

Seeking students to contribute to research exploring motor-disease protein complexes and their role in intracellular transport, as they relate to disease initiation and the aging process, and the ...

As spindly, elongated cells, neurons must be able to transport proteins and receptors between distant sites in their cell bodies and axons to function properly. A new imaging study by researchers at ...

Background The mechanisms by which huntingtin induces dysfunction and death of neurons in the brain are not clearly understood but they involve in part the loss of the protective properties of ...

Carnegie Mellon University's Jessica Zhang and Angran Li have developed a new way to model material transport regulation in neurons, focusing on the "traffic jams" that occur in these neural pathways.

RNA granules, sites for the storage, transport, and regulation of RNA molecules within cells, are transported along axons and then translated locally, far from the cell body. Recent studies suggest ...

To allow for the local translation of proteins that suit the ever-changing needs of the axon, neurons must ship transcripts from the soma to their outermost reaches. For thousands of these mRNAs, ...

Tara M. DeSilva from the Department of Neurosciences, Cleveland Clinic, examines the link between white matter lesions and neurodegeneration Magnetic resonance imaging (MRI) is a non-invasive ...