The Hughes Fire near Castaic, California, has burned over 5,000 acres, prompting evacuations and school closures.
"A strong Santa Ana Wind event is expected to develop Monday and last through at least Tuesday," the National Weather Service said.
After a weekend of reprieve allowing fire teams to continue making progress battling the deadly infernos burning in Los Angeles County, Southern California now faces another round of fire-fueling Santa Ana Winds Monday.
The Los Angeles haven’t spread in nearly a week, but the return of the Santa Ana winds to full strength could cause problems.
Santa Ana winds finally delivered a big, direct hit on San Diego County Tuesday, gusting as high as 102 mph in the backcountry where a touch of long-overdue rain could arrive this weekend.
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Much of inland San Diego County was whipped yet again by a strong Santa Ana wind event Monday into Tuesday, contributing to risky fire conditions as the region remains bone-dry.
After a much quieter weekend, Southern California is experiencing a major shift in the weather pattern. The winds will peak Monday evening and overnight but extend into Tuesday morning.
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Santa Ana winds timeline
Extreme fire weather returns to Southern California - particularly Los Angeles and Ventura counties - as winds of up to 100 mph have prompted the most urgent warning from the National Weather Service.
Rain returned to California over the weekend, aiding with the ongoing wildfire fight across the LA area. But the arrival of rain also brought the risk of flash flooding and mudslides in recent burn scar areas.
The Eaton and Palisades fires have consumed more than 37,000 acres of homes, businesses and landmarks in Altadena and Pacific Palisades.