A nerve cell resembles a vast tree with branches that communicate with thousands of other cells. To function, it depends on a ...

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

Centralspindlin is a heterotetrameric protein complex consisting of dimeric kinesin-6 (Pavarotti or Pav-KLP in Drosophila melanogaster (Pav/kinesin-6), ZEN-4 in Caenorhabditis elegans and CHO1/MKLP1 ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

Zachary Gergely, Michele Jones, Bojun Zhou, Cai Cash, J. Richard McIntosh, and Meredith D. Betterton (2023). Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone ...

Researchers detail the mechanism that allows propofol, a common anesthetic, to halt the movement of kinesin proteins that deliver cargoes to the far reaches of cells. Like a wrench that gums up the ...

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

HOUSTON - (Jan. 28, 2021) - Like a wrench that gums up the gears, a common anesthetic keeps the motor proteins in your cells from making their rounds. This is not necessarily a bad thing, but how it ...