Major depressive disorder shares immune abnormalities and potential therapies with inflammatory skin diseases

A team of leading clinical research scientists from the Departments of Psychiatry and Dermatology at the Icahn School of ...
BioWorld

Hansoh Pharma and Hansoh Bio synthesize new muscarinic M4 receptor agonists

Jiangsu Hansoh Pharmaceutical Group Co. Ltd. and Shanghai Hansoh Biomedical Co. Ltd. have discovered heterocyclic carbonyl derivatives acting as muscarinic M4 receptor agonists potentially useful for ...
News-Medical.Net

Engineered CAR-T cells reduce Alzheimer’s plaques in mice

T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers.

Engineered immune cells help reduce toxic proteins in the brain

T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option ...
BioWorld

The United Bio-Technology discloses new GLP-1R agonists

Co. Ltd. has reported compounds acting as glucagon-like peptide 1 receptor (GLP-1R) agonists. They are reported to be useful for the treatment of diabetes type 1, gout, psoriasis, stroke, inflammatory ...

Low-Dose THC May Help Protect the Gut and Liver in HIV

Tiny, non-intoxicating doses of THC may help protect the body from the long-term side effects of HIV treatment.
Frontiers

Enhancing anti-tumor immunity through co-blocking PD-L1 and TIGIT by facilitating tumor-directed responses and additional VEGF inhibition

Combination therapy targeting the PD-1/PD-L1 and TIGIT pathways has been explored to enhance the efficacy of current immunotherapies. In this study, we investigated strategies to further potentiate ...
Nature

Biosensors characterize the routes taken by receptors to different active states

A panel of fluorescently labelled G-protein-coupled-receptor proteins expressed in living cells has confirmed that, when bound by an activating ligand molecule, these receptors form different ...