After a brutal three-game road trip, the Sixers will return home on Friday night as losers of seven contests in a row. Things will not get any easier, as they will face the Eastern Conference-best Cleveland Cavaliers, who trashed the Sixers in Cleveland last month.

The Cleveland Cavaliers head to Wells Fargo Center to face the Philadelphia 76ers in an Eastern Conference matchup. The Cavs are 36-7, which puts them in first place, and gives them the best record in the NBA. The Sixers are 15-27, which puts them in 11th place.

James maintains strong ties to his home state of Ohio. He is from Akron and began his NBA career with the Cleveland Cavaliers. Philadelphia Phillies star Bryce Harper also was on hand. The two-time National League MVP also was here to cheer for the Buckeyes.

Analyzing Friday’s Cleveland Cavaliers at Philadelphia 76ers odds and lines, with NBA expert picks, predictions and best bets.

LeBron James was in attendance at Mercedes-Benz Stadium to watch his beloved Ohio State Buckeyes play Notre Dame for the College Football Playoff championship

On Friday night in South Philly, the Philadelphia 76ers will host the Cleveland Cavaliers for their third matchup this season. The game will lack some key playe

Los Angeles Lakers superstar LeBron James and Philadelphia Phillies slugger Bryce Harper were in attendance for Monday night's College Football

Darius Garland scored 22 points, Donovan Mitchell added 21 and the Cleveland Cavaliers snapped a season-high, three-game losing streak with a 110-91 win over the Detroit Pistons.

Northeast Ohio will be well represented when the Kansas City Chiefs and Philadelphia Eagles kickoff from New Orleans on Sunday, Feb. 9, in Super Bowl LIX.

The Cleveland Cavaliers have dominated in the East this season at 37-9 with consistent top performances, while talented Philadelphia has unexpectedly struggled.

Paul George and the Philadelphia 76ers react to snapping their losing skid in a win over the Cleveland Cavaliers at home.