If a person with no cognitive complaints tests positive for brain amyloid based on plasma p-tau217, what should their doctor tell them about their likelihood of getting Alzheimer’s disease? That’s the ...

The A673T (“Icelandic”) mutation in APP is associated with protection against Alzheimer's disease and age-related cognitive decline. This knock-in rat model carries the Icelandic mutation and a ...

The Alzheimer’s disease field has been abuzz about plasma p-tau217 for a while. This marker of brain amyloid can identify, with a high degree of accuracy, people with AD pathology among the ...

The center does not accept donations. Collection is limited to participants in longitudinal research projects conducted by the center. Phenotypes collected include Alzheimer's disease, cognitively ...

Contact Information Tugce Munise Satir, Master's, Ph.D. student Gothenburg, Sweden Education ...

As awareness about dementia continues to grow worldwide, a spate of online courses aims to help both health professionals and the general public understand Alzheimer’s and related diseases. Below is a ...

These parkin knockout (KO) mice were generated by creating a germline disruption in the parkin gene within exon 3 leading to a truncated transcript coding for the first 95 amino acids of mouse parkin ...

This mouse model was developed to investigate the effects of PINK1 deficiency (Kitada et al., 2007). The model involves a germline deletion of exons 4-7 of the endogenous Pink1 gene, creating ...

The decade-long Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) study wrapped up this month. According to top-line results announced March 8 by Eli Lilly, more than four years of ...

Score another one for amyloid immunotherapy. The anti-pyroglutamated amyloid antibody donanemab has posted positive top-line results in the Phase 3 Trailblazer-Alz2 study, according to an Eli Lilly ...

A top researcher’s fall from grace sends shock waves through the scientific community. Such is the case with neuropathologist Eliezer Masliah, who stands accused of image falsification spanning 26 ...

Introduction Despite being arguably the second most common dementing disorder, dementia with Lewy bodies, aka DLB, remains both mysterious and understudied. On Tuesday, October 10, 2017, the Lewy Body ...