Fred Hutch

Vector Production

As a lab within the Cooperative Center of Excellence in Hematology (CCEH) at Fred Hutch, the Vector Production core assists investigators with the design, construction, and/or production of viral ...
Nature

Lentiviral Vector Production and Gene Therapy Applications

Lentiviral vectors have emerged as indispensable tools in gene therapy, offering the ability to integrate therapeutic genes into both dividing and non-dividing cells. Their unique capacity to achieve ...
GEN

Transferring Viral Vector Production from Plasticware to a Fixed-Bed Bioreactor

Gene and modified cell therapies (for example, chimeric antigen receptor [CAR] T-cell therapies) in early to late clinical development are showing significant promise to treat and potentially cure ...
GEN

Vector Production Would Benefit from Purpose-Built Processing Technology

Demand for lentiviral vectors will continue to outstrip supply until the industry has access to more efficient, purpose-built manufacturing and bioprocessing technologies. The warning comes from ...
FiercePharma

Vexed by vectors: How COVID-19 vaccine and cell and gene players are tackling the viral vector bottleneck

Bristol Myers Squibb’s cancer cell therapy Breyanzi. Johnson & Johnson and AstraZeneca’s recombinant COVID-19 vaccines. Novartis’ gene therapy Zolgensma. All of these, plus many others, are united by ...