Viruses are sneaky intruders, hijacking the internal machinery of host cells and replicating out of sight. Understanding these dynamics is the first step to developing effective antiviral strategies ...

A new review maps the orthohantavirus life cycle for chemotherapeutic intervention, evaluating entry inhibitors, polymerase ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated ...

Scientists have identified dozens of human proteins that SARS-CoV-2, the virus that causes COVID-19, depends on to replicate and spread, according to a recent study published in the journal PLOS ...

The development of effective treatment strategies for human immunodeficiency virus (HIV) infection is a major achievement. Antiretroviral drugs inhibit key steps in the viral replication cycle and ...

Researchers at Umeå University have identified two human cell proteins, NUP98 and NUP153, that play a crucial role in how viruses such as tick-borne encephalitis virus (TBEV), West Nile virus, and ...

Researchers at Radboud University Medical Center report that prolyl hydroxylation of Zika virus NS1 is essential for the protein's maturation and secretion, revealing a new host-dependent step in ...

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...