New research headed by scientists at the Centre for Genomic Regulation (CRG) has demonstrated how the three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary ...

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Proteins, the natural molecules that carry out key cellular functions within the body, are the building blocks of all diseases. Characterizing proteins can reveal the mechanisms of a disease, ...

Biologists found a way to identify and study low-complexity regions of proteins. The technique allows them to analyze similarities and differences between LCRs from different species, and helps ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...

A multicolored protein structure is blurred at the edges and comes into focus toward the center. Detail of a protein designed using a tool called ProteinMPNN Credit: Ian C. Haydon/UW Institute for ...