Variable number tandem repeats (VNTRs) were among the first genetic markers used to quantitate bone marrow transplant engraftment. The limitations of PCR-based VNTR markers in distinguishing some ...
Abstract: Chimerism analysis is a surrogate indicator of graft rejection or relapse after allogeneic hematopoietic stem cell transplantation (HSCT). Although short tandem repeat PCR (STR-PCR) is the ...
We have recognized a number of problems, inherent in the STR-PCR technology, which may affect the eligibility of markers for chimerism testing and the accuracy of quantitative analysis. These are as ...
Human sample identification is an essential element of many research projects employing human cells, tissues, or mixtures. Identification may be required to track and confirm sample provenance for ...