Molecular machinery in cardiac mitochondria reacts to metabolic stress in unexpected way

In a recent study published in Nature Communications, researchers at Karolinska Institutet report that the molecular machinery responsible for cellular energy conversion is more interconnected than ...
EurekAlert!

Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha regulates vascular remodeling and progression of aortic dissection

Aortic dissection (AD) is a life-threatening cardiovascular emergency characterized by rapid onset and progression, with limited clinical intervention options. Lactate, a glycolytic metabolite, has ...
Science Daily

Recommendations for mitochondria transfer and transplantation research

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...
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Researchers just cracked why aging cells quietly lose their energy — mitochondria drop the outer sacs that once protected them, and the rest of the cell follows

Every cell in your body runs on a currency called ATP, and the factories that mint it are mitochondria. For decades, scientists knew those factories deteriorated with age. What they could not explain ...
Medical Xpress

Mitochondria may be a promising therapeutic target for inflammatory diseases

Scientists in the laboratory of Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the ...