Over the years, bioprocessors could, at various times, debate whether upstream or downstream operations represented the slow step, relatively speaking, of therapeutic protein production. Now, with ...

Although technologies have advanced significantly since the first approval was given for a clinical trial of a gene therapy product in 1990, many challenges remain. 1 Among them is the need for fast, ...

Today, crystallization is used primarily to analyze the structures of proteins. It also is gaining favor as a purification method for elastase, proteases, albumin, and lipase, in addition to ...

Adeno-associated viruses (AAVs) have emerged in recent years as a crucial tool in clinical gene therapies, offering low pathogenicity and long-lived gene expression in target cells. AAVs are simple ...