hiPSCs are increasingly used in cardiovascular research, including in disease modeling, cardiotoxicity screening, drug discovery and the study of human cardiac development 1. Furthermore, a major aim ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time. Researchers at Sylvester Comprehensive Cancer Center (FL, USA) have ...

Numerical integration and differentiation techniques are commonly used in engineering, particularly when analyzing experimental data. Integration and differentiation of measured response signals can ...

Stem Cell Technology Can Facilitate Quick & Early Failure of Toxic or Ineffective NCEs One axiom of the pharmaceutical industry is to “fail fast and fail early,” thereby minimizing investment in toxic ...

Parkinson's disease, a common neurodegenerative ailment, affects roughly 1 % of the population aged 60 and up, and the number of cases is anticipated to quadruple by 2040, posing a significant ...

This paper demonstrates applications of automatic differentiation with nested dual numbers in the diffusion operator integral variance-reduction framework originally proposed by Heath and Platen.

Neurodegenerative diseases like Parkinson's and Alzheimer's are characterized by irreversible neuron damage and limited natural repair mechanisms. While stem cell therapy holds great promise for ...

A team of biologists has shone a light on the complex evolution of sexual differentiation in different species of frog from the family Pipidae. Invariant phenotypes, where the phenotype remains ...