Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

Have you ever come across the term "NGS" in articles about cancer gene panel testing or whole-genome analysis?NGS is a technology that reads DNA base sequences in large quantities.While conventional ...

Researchers at Beijing Genomics and IMDEA Nanociencia institutes have introduced a novel method that could significantly accelerate efficiency and reduce the cost of handling fluidics in DNA ...

Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are ...

University of Michigan researchers used long-read nanopore sequencing to resolve hidden cancer-driving alterations in tumors ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

The fastest DNA sequencing technique is 3 hr 58 min 59 sec, and was achieved by Broad Clinical Labs, Roche Sequencing Solutions, Inc., & Boston Children's Hospital (all USA) in Burlington, ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...

A prospective South Korean cohort study found that plasma microbial cell-free DNA metagenomic sequencing substantially agreed ...

Two identical sisters came into the world carrying the same rare cancer. They lost their lives to an undifferentiated sarcoma ...