Clemson is a 4-point favorite against LSU, according to the VegasInsider.com consensus betting line. That's an uptick from the game's opening point spread (Clemson -2.5). A few sportsbooks, including FanDuel, have Clemson as a 4.5-point favorite.

Here's who will have the call of Saturday's top 10 showdown in Death Valley when No. 4 Clemson hosts No. 9 LSU in prime time.

There are still tickets remaining for this primetime top-10 game. The cheapest ticket available is $305. The cheapest seat in the lower level is $416. To see a full list of ticket prices, visit StubHub. Here is the entire 2025 Clemson football schedule.