Human cells are organized across a spatial hierarchy of components, ranging from small protein complexes at the scale of nanometres to large condensates, compartments and organelles at the scale of ...

The brain is a complicated network of connections and functions, but its inner machinations remain an enigma. In a huge collaborative effort, researchers profiled millions of cells to chart a cellular ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Researchers developed an AI tool that links cellular structure changes to drug effects by analyzing biomolecular condensates.

Cryogenic electron microscopy (cryo-EM) has now been widely used for determining multichain protein complexes. However, modeling a large complex structure, such as those with more than ten chains, is ...

One of the ultimate goals of biological research is to understand the multiscale organization of the human cell and its relationship to biological function and human disease. As much of cell structure ...

Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections and tumors. For these processes to function properly, immune cells (B cells ...

The centre is building a platform that works like Google Earth of human brain ...