In the 20 years since the FDA’s approval of rituximab for rheumatoid arthritis, trials and real-world use of B-cell depleting therapies have resulted in surprising successes and unexpected setbacks in ...

One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated ...

Scientists have long understood that parts of cells, called organelles, evolved to have certain shapes and sizes because their forms are closely related to how they function. Now, Johns Hopkins ...

B-cell chronic lymphocytic leukemia (CLL) occurs when abnormal B cells accumulate in the bone marrow and blood. This crowds out healthy blood cells and weakens the body’s ability to fight infections.

Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many components of the cell still remain uncharted. " We know each of the proteins ...