A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and ...
Organisms sense and respond to changes in the environment through signal transduction pathways. Pathways like highly conserved Mitogen-Activated Protein Kinase (MAPK) pathways are composed of sensor ...
(Upper panel) Normal podocytes: Ephrin-B1 at slit diaphragm interacts with nephrin via the extracellular site and with Par6 via the cytoplasmic site. (Lower panel) Podocytes stimulated by anti-nephrin ...
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