The Financial

Hepatic Cannabinoid Signaling in the Regulation of Alcohol-Associated Liver Disease

Apart from the CB1R antagonist, the pharmacological potential of the CB2R agonist, which is known to have hepatoprotective effects, also has been reevaluated. 36 Although only observed in mice, a ...
FierceBiotech

Polyrizon pays $3M for license to SciSparc's preclinical cannabinoid pain therapy

Israeli biotech SciSparc has sold the license for its cannabinoid receptor type 2 (CB2R) agonist to its partner Polyrizon to further develop as a pain therapy. The agreement will see Polyrizon secure ...
Science Daily

Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury, study suggests

A new study suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia. A new study published in the March issue of The American ...
BioWorld

RG-7774, a novel CB2 receptor agonist with potency and efficacy across species

Researchers from Roche Holding AG disclosed the discovery and preclinical evaluation data for RG-7774 (vicasinabin), a novel cannabinoid CB2 receptor (CB2R) agonist being developed for the treatment ...
Labroots

Study Explores Role of Cannabinoid Receptor Type 2 Activity in Granulocyte Colony-Stimulating Factor (G-CSF) Treatment for Traumatic Brain Injury (TBI)

A study published in the Journal of Cannabis Research examined the effect of granulocyte colony-stimulating factor (G-CSF) on brain recovery following traumatic brain injury (TBI). The findings showed ...