On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
Giving Structure to Language: Profluent’s AI Models Move toward Precise and Steerable Protein Design
The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...
Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...
For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...
A protein’s amino acid sequence helps determine its structure. Thus, proteins with similar sequences would be expected to have similar structures. But sometimes seemingly minor sequence changes can ...
When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...
In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback