Hypertension affects 1 in 3 adults globally and is the leading modifiable risk factor for cardiovascular disease. Aldosterone dysregulation, often driven by obesity and primary aldosteronism, affects ...

Nine normal volunteer subjects (6 males and 3 females), nineteen to thirty-six years of age, and 5 patients with primary aldosteronism (3 females and 2 males), forty to fifty-two years of age, were ...

A team of medical researchers and doctors affiliated with multiple institutions in the U.S. has found, via clinical trial, that the aldosterone synthase inhibitor lorundrostat is likely safe to use ...

Exercise cannot reduce a sodium-retaining hormone, aldosterone, which is known to potentially cause hypertension in African Americans. Many African Americans develop the salt-sensitive form of ...