The only thing keeping Houston from an even higher standing during March Madness is a national title. The Cougars have a shot at it this year, though they're just the fifth most-bet team to win it all at BetMGM,

With NCAA tournament First Four games beginning Tuesday, March Madness is here. And that means it's time for some predictions. Who will advance out of each region and get to the Final Four in San Antonio?

Houston looks to begin their March Madness run as they face SIUE. It’s time to continue our College Basketball odds series with an SIUE-Houston prediction and pick. SIUE was 22-11 this year while going 13-7 in conference play.